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Dr. Seerapani Gopaluni is an expert nephrologist specializing in kidney health and transplantation. With over 20 years of experience, he delivers personalized, advanced care. His focus is on improving patient outcomes through comprehensive diagnosis and treatment of kidney diseases.

Contact Info

9th floor, Apollo Tele Health Services Apollo Health city, Lifesciences Building, Jubilee Hills, Hyderabad, Telangana 500033

How Polycystic Kidney Disease Affects Your Body

How Polycystic Kidney Disease Affects Your Body

A person may go through his whole life without a warning sign. Then, small changes start to appear. Tiredness, ache in the back or blood pressure that slowly shows up. What no one sees is tiny cysts growing over the years, slowly affecting how the kidneys work.

What Is Polycystic Kidney Disease?

PKD is a genetic disorder. In this disease, numerous cysts develop within the kidneys. These cysts become bigger and increase in number slowly damaging the kidney functions.

There are two main types:

  • Autosomal Dominant PKD (ADPKD): The common type. The first signs normally begin at adulthood.
  • Autosomal Recessive PKD (ARPKD): Uncommon and are often found in children.

Eventhough, PKD is a genetic condition, the disease development is affected by the lifestyle.

How PKD Affects Your Body

PKD primarily involves the kidneys, however, as the cysts increase in size, the disease may affect numerous other areas of your body as well.

Kidneys

The increasing cysts cause the kidneys to be large and heavy. Over time, you may experience:

  • Pain in the back or sides
  • Blood during urination (when a cyst ruptures)
  • Repeated kidney infections
  • Slow damage of kidney functions
  • Fatigue, vomiting, leg swellings can occur with a decrease in kidney functions

High Blood Pressure

Majority of patients with PKD develop high blood pressure.

This occurs due to the fact that the kidneys greatly contribute towards the regulation of BP, which cysts disrupt.

High BP may also cause severe kidney damage therefore, it is highly important to manage it.

Liver Cysts

The cysts in the liver are also common in many individuals with ADPKD.

These cysts will not normally influence liver functioning, although they might result in:

  • Fullness in the stomach
  • Bloating
  • Discomfort after eating

Blood Vessels

There are also individuals with PKD who might develop weak spots within the blood vessels particularly in the brain which is commonly known as aneurysms. They are not common but they must be addressed in case you have a family history.

Stomach and Abdomen

The larger the kidneys the larger they become and thus occupy more space in the abdomen.

This can cause:

  • Bloating
  • Early fullness while eating
  • Difficulty sleeping comfortably

Pain

Pain is one of the most common symptoms. It is caused by:

  • Large cysts
  • Bursting cysts
  • Kidney stones
  • Infections

Pain may be mild or severe, but it can be managed with proper care.

Symptoms to Watch Out For

PKD symptoms usually appear slowly. Signs may include:

  • Pain in back, sides or abdomen
  • Frequent urination
  • Blood in urine
  • Swelling in legs or feet
  • High blood pressure
  • Headaches
  • Repeated urine infections
  • Tiredness or weakness
  • Increase in waist size due to enlarged kidneys

Managing PKD: What Really Helps

PKD cannot be cured at the moment, but there are numerous methods and ways of treatment, and habits that make this disease less impactable.

Control Blood Pressure

This is the most important step.

It is better to maintain BP at 120/80 in the majority of PKD patients.

Drink Plenty of Water

Hydration helps slow down the hormone that promotes cyst growth.

Your doctor will tell you how much water is right for you.

Simple steps make a big difference:

  • Reduce salt
  • Eat fresh foods
  • Avoid smoking
  • Walk or exercise regularly
  • Avoid painkillers like ibuprofen
  • Maintain a healthy weight

Treat Infections Quickly

If you have fever, pain, or burning urine, get checked immediately.

Infections can worsen kidney damage if ignored.

If you’re looking to protect your kidney health or manage an existing kidney concern, expert guidance makes all the difference. Dr. Seerapani provides patient friendly, personalised renal diet and lifestyle advice based on your health needs and lab reports.

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Dr. Seerapani Gopaluni

Expert Nephrologist at Apollo Hospitals